High molecular weight caldesmon expression in ovarian adult granulosa cell tumour and fibrothecoma
نویسندگان
چکیده
منابع مشابه
DiVerential expression of high molecular weight caldesmon in colorectal pericryptal fibroblasts and tumour stroma
Aim—To investigate an extent of smooth muscle diVerentiation of pericryptal fibroblasts. Methods—Expression of high molecular weight caldesmon (h-CD) and á smooth muscle actin was investigated in 123 invasive colorectal adenocarcinomas and their surrounding non-neoplastic tissues. Results—The monoclonal antibody to h-CD, which showed predominantly positive immunostaining in well diVerentiated s...
متن کاملDifferential expression of high molecular weight caldesmon in colorectal pericryptal fibroblasts and tumour stroma.
AIM To investigate an extent of smooth muscle differentiation of pericryptal fibroblasts. METHODS Expression of high molecular weight caldesmon (h-CD) and alpha smooth muscle actin was investigated in 123 invasive colorectal adenocarcinomas and their surrounding non-neoplastic tissues. RESULTS The monoclonal antibody to h-CD, which showed predominantly positive immunostaining in well differ...
متن کاملUnusual and late recurrences in ovarian adult granulosa cell tumours.
Case 1 A 47-year-old woman presented 13 years after laparotomy for a malignant GCT. She had undergone total abdominal hysterectomy, bilateral salpingo-oophorectomy (TAH+BSO) and omentectomy for a stage I disease according to the classifi cation by the Federation of International Society of Gynaecologists and Obstetricians (FIGO). Histology had confi rmed the type and stage of the malignancy. Co...
متن کاملHigh molecular weight caldesmon positive stromal cells in the capsule of thyroid follicular tumours and tumour-like lesions.
AIMS To investigate the smooth muscle nature of the spindle stromal cells in the capsule of thyroid tumours and tumour-like lesions. METHODS Immunostaining for high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle differentiation, was performed in 70 primary thyroid tumours and tumour-like lesions (21 hyperplastic nodules, 29 follicular adenomas, five minimally inv...
متن کاملThe molecular mechanism of ovarian granulosa cell tumors
Over these years, more and more sex cord-stromal tumors have been reported. Granulosa cell tumor (GCT) is a rare tumor in ovaries, accounts for 2% to 5% of ovarian cancers. The main different feature of GCTs from other ovarian cancers is that GCTs can lead to abnormally secreted hormones (estrogen, inhibin and Müllerian inhibiting substance). The GCT is divided into two categories according to ...
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ژورنال
عنوان ژورنال: Histopathology
سال: 2017
ISSN: 0309-0167
DOI: 10.1111/his.13365